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AG Oehmcke-Hecht


Contact

Dr. rer. nat. Sonja Oehmcke-Hecht

Dr. rer. nat.

Sonja Oehmcke-Hecht 

  • Nachwuchsgruppenleiterin
    am Institut für Medizinische Mikrobiologie, Virologie und Hygiene

+49 (0) 381 494 5906
+49 (0) 381 494 5794
+49 (0) 381 494 5902 

sonja.oehmcke{bei}med.uni-rostock.de


Büro

Raum: 263

Universitätsmedizin Rostock
IMIKRO
Schillingallee 70
D-18057 Rostock

Sekretariat

Gudrun Riedel

  • Sekretärin
    am Institut für Medizinische Mikrobiologie, Virologie und Hygiene

+49 (0) 381 494 5919
+49 (0) 381 494 5925

gudrun.riedel{bei}med.uni-rostock.de

Raum: 112, EG

Publikationen

Wissenschaftlicher Werdegang

Dr. rer. nat. Sonja Oehmcke-Hecht


seit April 2017 

Nachwuchsgruppenleiterin
im Rahmen der Landesexzellenzinitiative MV
IMIKRO, Universitätsmedizin Rostock, Deutschland

Mai/2016-Mär/2017Wissenschaftliche Projektleiterin
IMIKRO, Universitätsmedizin Rostock, Deutschland
Sep/2011-Mai/2016

Wissenschaftliche Projektleiterin
(DFG “eigene Stelle“)
IMIKRO, Universitätsmedizin Rostock, Deutschland

Okt/2010-Jul/2011

Wissenschaftlerin an der Universität Lund
Department of Clinical Sciences
Division of Infection Medicine, Lund, Sweden

Sep/2008-Sep/2010

Postdoc (Marie Curie EU Scholarship)
Department of Clinical Sciences
Division of Infection Medicine, Lund, Sweden

Sep/2006-Aug/2008

Postdoc an der Universität Lund
Department of Clinical Sciences
Division of Infection Medicine, Lund, Sweden

Jan/2002 -Jul/2006Doktorarbeit
Prof. Dr. Dr. Podbielski
IMIKRO, Universitätsmedizin Rostock, Deutschland

AG Oehmcke-Hecht

location

Anfahrt zum IMIKRO

Bild bitte anklicken

Main Topics

Modulation of the human coagulation system by bacteria and viruses (KoInfekt)

The hemostatic system comprises platelet aggregation, coagulation and fibrinolysis and is a host defense mechanism that prevents bleeding after vessel injury. During systemic infection complications occur because of a dysregulated coagulation system. While this is widely accepted, an important role of the coagulation system in the early host response to infectious diseases has been only recently begun to be appreciated. The induction of coagulation entraps microorganisms in a fibrin clot and inhibits pathogen dissemination and survival, indicating that interaction of bacteria or viruses with the coagulation system may be an integral part of the innate immune response.

Our research is focused on a molecular understanding of strategies that are used by bacteria to subvert immune defense and how the innate immune system responds to bacterial and viral invaders. Such studies will expose fundamental functions of the immune system and identify new targets for the treatment of severe infectious diseases.

The role of the human contact system during sepsis (DFG supported)

The general aim of this project is to identify the function of human contact factors during invasive streptococcal infection and define the relative contributions of the intrinsic and extrinsic coagulation pathway in streptococcal sepsis. The findings of this application will help to identify novel diagnostic tools or targets for the treatment of severe infectious diseases.

Interaction of Streptococcus gallolyticus with colorectal cancer cells

S. gallolyticus (Sg) is often associated with colorectal cancer, and patients with Sg infections display a much higher risk of having colorectal cancer compared to the general population. It was recently shown that Sg promotes human colon cancer cell proliferation, pointing to a tumor-promoting role of Sg. Beside this it was described that Sg could be considered so far, the best bacterial cellular factories for tannin degradation. We showed that tannine are toxic against cancer cells and will further investigate whether tannin degradation by Sg play a role in tumor protection.

Group

Group leader

Dr. rer. nat.

Sonja Oehmcke-Hecht 

  • Nachwuchsgruppenleiterin
    am Institut für Medizinische Mikrobiologie, Virologie und Hygiene

+49 (0) 381 494 5906
+49 (0) 381 494 5794
+49 (0) 381 494 5902 

sonja.oehmcke{bei}med.uni-rostock.de


Büro

Raum: 263

Universitätsmedizin Rostock
IMIKRO
Schillingallee 70
D-18057 Rostock

Sekretariat

Gudrun Riedel

  • Sekretärin
    am Institut für Medizinische Mikrobiologie, Virologie und Hygiene

+49 (0) 381 494 5919
+49 (0) 381 494 5925

gudrun.riedel{bei}med.uni-rostock.de

Raum: 112, EG

Publikationen

Wissenschaftlicher Werdegang

Dr. rer. nat. Sonja Oehmcke-Hecht


seit April 2017 

Nachwuchsgruppenleiterin
im Rahmen der Landesexzellenzinitiative MV
IMIKRO, Universitätsmedizin Rostock, Deutschland

Mai/2016-Mär/2017Wissenschaftliche Projektleiterin
IMIKRO, Universitätsmedizin Rostock, Deutschland
Sep/2011-Mai/2016

Wissenschaftliche Projektleiterin
(DFG “eigene Stelle“)
IMIKRO, Universitätsmedizin Rostock, Deutschland

Okt/2010-Jul/2011

Wissenschaftlerin an der Universität Lund
Department of Clinical Sciences
Division of Infection Medicine, Lund, Sweden

Sep/2008-Sep/2010

Postdoc (Marie Curie EU Scholarship)
Department of Clinical Sciences
Division of Infection Medicine, Lund, Sweden

Sep/2006-Aug/2008

Postdoc an der Universität Lund
Department of Clinical Sciences
Division of Infection Medicine, Lund, Sweden

Jan/2002 -Jul/2006Doktorarbeit
Prof. Dr. Dr. Podbielski
IMIKRO, Universitätsmedizin Rostock, Deutschland

AG Oehmcke-Hecht

Team

MSc

Juliane Köhler

  • Phd-Student
    am Institut für Medizinische Mikrobiologie, Virologie und Hygine

+49 (0) 381 494  5920
+49 (0) 381 494  5794
+49 (0) 381 494  5902

juliane.koehler{bei}med.uni-rostock.de

Büro:    260,  1. OG

Elisabeth AleithHIWI+49 (0) 381 494 5939

Technical assistant

Jana Bull

  • Medizinisch-technische Assistentin in der Forschung
    am Institut für Medizinische Mikrobiologie, Virologie und Hygiene

+49 (0) 381 494 5799
+49 (0) 381 494 5794
+49 (0) 381 494 5795
+49 (0) 381 494 5902

jana.normann{bei}med.uni-rostock.de

Labor: 004A, KG
Büro:     101, EG

Alumni

Dr. rer.nat. Ramona Nitzsche
Dr. med. Carolin Trepesch