Infection Immunology


Dr. rer. nat.

Sonja Oehmcke-Hecht 

  • Wissenschaftlerin

    am Institut für Medizinische Mikrobiologie, Virologie und Hygiene

+49 (0) 381 494 5906
+49 (0) 381 494 5794
+49 (0) 381 494 5902 



Raum: 263

Universitätsmedizin Rostock
Schillingallee 70
D-18057 Rostock


Gudrun Riedel

  • Sekretärin
    am Institut für Medizinische Mikrobiologie, Virologie und Hygiene

+49 (0) 381 494 5919
+49 (0) 381 494 5925


Raum: 112, EG


Beruflicher Lebenslauf / Curriculum Vitae

Dr. rer. nat. Sonja Oehmcke-Hecht

1973 born
  Married, two kids


1990-1993 medical technical assistant (MTA) in Greifswald, Certification: MTA
1996-2001 Study of Biology, University of Rostock, Germany
12/2001 Master of Science, title:
"Transcription analysis of the pst Operon from Clostridium acetobutylicum"
Prof. Dr. Bahl, Department of Bio- sciences, Microbiology, University Rostock, Germany

grade: sehr gut

2002-2006 Graduate (Ph.D.) student Doctoral thesis:
"Characterization of Fibronectin- and Collagen-binding proteins of Streptococcus pyogenes"
Prof. Dr. Dr. Podbielski, Department of Medical Microbiology and Hospital Hygiene, University Rostock, Germany

grade: summa cum laude

2003-2004 parental leave
2013-2014 parental leave

Employment history

1993-1995 medical technical assistant in Rostock and Borstel
2006-2008 Postdoctoral position, Lund University, Sweden
2008-2010 Postdoctoral position, (Marie Curie EU Scholarship), Lund University, Sweden
2010-2011 Scientist, Lund University, Sweden
since 2011 Scientific project leader, Rostock University, Germany

AG Oehmcke-Hecht


Main Topics

The haemostatic system comprises platelet aggregation, coagulation and fibrinolysis and is a host defense mechanism that prevents bleeding after vessel injury. During systemic infection complications occur because of a dysregulated coagulation system. While this is widely accepted, an important role of the coagulation system in the early host response to infectious diseases has been only recently begun to be appreciated. The induction of coagulation entraps microorganisms in a fibrin clot and inhibits pathogen dissemination and survival, indicating that interaction of bacteria with the coagulation system may be an integral part of the innate immune response.

Our current and future research is focused on a molecular understanding of how the innate immune system responds to bacterial invaders, and which strategies are used by bacteria to subvert immune defense. In addition, we study development and functions of infected monocytes, a type of white blood cells and part of the innate immune system. Such studies will expose fundamental functions of the immune system and identify new targets for the treatment of severe infectious diseases.


Working groups in this area